When school teacher Catherine Edwards missed a family outing, her worried parents went to her apartment to check on her. There, they made the horrifying discovery: Catherine had been restrained with law enforcement style handcuffs and murdered. Investigators followed dozens of leads as the alarmed community worried about a killer on the loose. Given the handcuffs, investigators even looked at fellow police officers but the case remained a mystery. Nearly three decades later, a team of dedicated detectives, a Texas Ranger, and forensic genealogists teamed up to catch an unlikely killer, finally bringing justice to the Edwards family and the city of Beaumont.

The sheriff's office responds to a 911 call from a distraught husband, who said his wife had killed herself with a gun. Once on the scene, detectives uncover chilling evidence that turned the case into a murder investigation.

In 2002, a blueberry farmer in Ottawa County, Michigan, made a shocking discovery in his fields: the severely burned and beaten body of a man inside a trunk. Despite exhaustive efforts, investigators were unable to identify him, and he became known only as "Jack in the Box." The case sat cold on investigators' desks until 2015, when a detective started receiving emails with clues about the victim's identity. Investigators followed the tips, finally unraveling the chilling details of a gruesome crime, and a calculated cover-up, leading to an international manhunt and an ultimate betrayal by family.

The cold-blooded murder of four family members in their own living room in a normally peaceful neighborhood shattered the local religious Sikh community. The wide-ranging investigation left many questioning if they truly knew their neighbors.

Rap musician Martell DeRouen, known as "Kardone," was found shot to death in his luxury apartment, the door locked from the inside. Detectives faced a challenging mystery as they investigated the puzzling murder.

A masked intruder stormed into a house party, murdering three young members of Detroit's LGBTQ community. As detectives worked to track down the killer, they uncovered a surprising and troubling motive.