Midnight Kiss follows a group of longtime gay best friends and their straight female bestie as they head to a beautiful desert home to celebrate New Year's Eve. One of their annual traditions is to play a game called Midnight Kiss, a sexy but ultimately dangerous challenge to find that special someone to help you ring in the New Year. As friendships have grown strained with secrets, jealousy and resentment, the group faces another challenge when a sadistic killer wants in on the game. Relationships are put to the test and truths are revealed as the night turns into a fight for survival.