Generations ago, humanity's war against the Cyberoid war machines left our planet a desolate wasteland. Now, dozens of "ecropolis" cities are scattered along the landscape. Life is a hyper-modern utopia inside of these artificial habitats. But someone has a different idea of utopia.

Mankind is dead, destroyed by the evil computer GORN. The only survivors are six young women, shot deep into space by the android Catty. The creation of an alien race, only she understands the terrible cycles of war and destruction that devastate our race. And only she foresaw the coming disaster. Now, as the Earth smolders, a single escape pod races away, bound for an unknown destination. But GORN is close behind, with a powerful pursuit ship and a squadron of fighters. Through brain surgery and cybernetic implants, GORN now inhabits the body of Nova, its human tool. But GORN is not limited to a single body or single location. Like a computer virus, GORN can transmit itself into any computer.

Two hundred years have passed since mankind defeated the MME army and its leader, the artificial intelligence G.O.R.N. Earth has suffered war once more at the hands of Genova, the leader of a genetically modified evolution of humans known as the Yuman, and the effects of that war are visible even today. People now live in domed cities, population control is on the forefront of concern, and the planets are linked by a singular computer network. Now, fate strikes Earth once more as a Yuman man unleashes G.O.R.N. into the network, reviving its desires to exterminate humanity from the entire universe! It's up to the aging android Catty and a team of women to help save all mankind once more!